Histamine, a part of the body’s biological defense system, is also found in many common dietary sources: fermented foods, fish, meat, cheese, vinegar, alcohol, and some fruits and vegetables. Other foods contain histidine, which is converted to histamine during digestion by certain bacteria in the gut. At healthy levels and in the right places, histamine is needed for a normal digestive process and sleep-wake cycle, and for a functioning immune system. On the other hand, too much histamine can cause unpleasant side effects like rashes, itching, stuffy nose, swelling, headache and gastrointestinal complaints.*
Each person’s level of sensitivity to histamine in food depends on the amount of histamine present and the effectiveness of the body’s natural histamine-metabolizing mechanisms. It may seem like the only way to avoid the unpleasant side effects of histamine sensitivity is to eliminate high-histamine foods altogether – but such a restricted diet can deprive the body of balanced nutrition and make it difficult to enjoy meals. A healthy gut is a key factor in normal histamine metabolism and healthy histamine levels throughout the body.*
Cells in the gut produce DAO (diamine oxidase), an enzyme that breaks down histamine in the digestive tract. In healthy individuals, DAO is responsible for keeping the majority of ingested histamine from ever reaching circulation in the body. A healthy gut microbiome containing a balanced variety of “good” bacteria (i.e. probiotics) is essential for maintaining a healthy gut barrier, and healthy cells in the gut barrier are needed to maintain normal DAO levels.*
ProBiota HistaminX is now packaged in a moisture-controlled, desiccated bottle for enhanced product stability and potency. This new packaging delivers unparalleled protection for live probiotic products, which are sensitive to outside moisture. A desiccant sleeve surrounds the product creating an impenetrable barrier, contributing to greater product stability over time. Research has shown this container system to be more effective than standard bottles containing desiccants or even blister packs.