Calcium D-Glucarate is calcium bound to d-glucaric acid, which is a natural compound produced in small amounts by the human body and is abundantly found in various plant foods such as broccoli, cabbage, kale, apples, oranges, and grapefruit. Research shows that d-glucaric acid derivatives such as calcium d-glucarate help support the body’s natural defense against toxins and excess steroid hormones.** Unlike glucaric acid, calcium d-glucarate is available as a supplement. Oral supplementation of calcium d-glucarate is an ideal way to provide the body with an efficient, slow-release source of its active metabolite, D-glucaro-1, 4-lactone.
During normal liver detoxification, some toxins, including hormones like estrogen, are cleared via glucuronidation – a process wherein a compound called glucuronic acid is attached to a toxin (e.g., excess estrogen) in order to create a substance that is more readily eliminated by the body. In the case of liver detoxification, the substrates are most often xenobiotic substances—things that are foreign to the body, such as pharmaceutical drugs and environmental pollutants—as well as compounds produced inside the body through natural biochemical processes, like excess male and female reproductive hormones, mineralcorticoids, glucocorticoids (like cortisol), bile acids, and more. Theses toxins and hormones, once bound to glucuronic acid, are then ready to be safely eliminated.